(1) A neutrophile peptide eucaryotic expression vector was constructed.

(2) AIM: To study the role of polymorphonuclear neutrophile(PMN) in lipopolysaccharide (LPS)- induced acute lung injury (ALI) and the protective effect of interleukin - 10(IL - 10) on ALI.

(3) In the laboratory examination the counting of WBC, neutrophile granulocyte increased, while leukomonocyte decreased. The renal function index, fibrinogen index became abnormal.

(4) The main adverse reactions were hematologic toxicity. The manifestations were : WBC, neutrophile granulocyte, blood platelet and hemoglobin all decreased, then was digestive canal symptoms.

(5) Conclusion We can estimate morbid state by the leukocyte count and the percent of neutrophile granulocyte with acute cerebral infarction patients.